YAEYAMA Premium Quality CHLORELLA
Outdoor cultivated and Highly nutritious Chlorella
No coloring, No flavoring, No preservatives





   Yaeyama Premium Quality Chlorella Line-Up  

Yaeyama Chlorella Powder & Tablets, 200mg, 250mg, 300mg, 400mg, 500mg, bulk packed
Yaeyama Chlorella Extract Liquid "C.G.F. - Yaeyama", OD100, retail packed
Yaeyama Chlorella Extract Liquid OD400, bulk packed
Yaeyama Chlorella Extract Powder OD1200, bulk packed


NUTRITIVE CONTENT
Yaeyama Chlorella is a storehouse of rich nutrients - chlorophyll, CGF, vitamins, minerals, protein, carbohydrates.
It has over 60% protein with essential amino acids, and provides vitamin A, Beta-carotene, vitamins B, C, E and K. Its minerals include calcium, iron, phosphorus, potassium, magnesium, and trace amounts of manganese, iodine and zinc.

The following figures show lutein content:

Yaeyama Chlorella Powder ............. 503mg/100g
Spinach ............................................. 10.2mg/100g
Cooked spinach ................................ 7.4mg/100g
Cabbage ........................................ 14.5mg/100g
Broccoli .............................................. 1.9mg/100g
Carrot ................................................ 0.26mg/100g
(Note) Yaeyama Chlorella contains lutein 50 times as much as spinach.
C.G.F. (Chlorella Growth Factor)
Distinguished for its C.G.F., rich in nucleic acids of RNA/DNA, it is known for cell renewal, growth, energy and health protecting system to both young and old.
Its RNA is found 17 times more than sardines.
Yaeyama chlorella contains chlorella extract
(=hot water soluble matter; C.G.F.) in the range of as much as 20 to 30%.
DIGESTIBILITY
Yaeyama Chlorella has a digestibility rate** as high as more than 80%, being processed with its exclusive 3-step procedures to break the cell walls, resulting in maximum absorption of the ingredients.
** Digestibility of chlorella protein by small animal assay procedures
1. Steaming under pressure for sterilization, cell dilation and cracks.
2. Heated air applied within the Spray Dryer for further cell wall cracks.
3. Jet Spray system for smashing at high impact velocity.
NO AGRICHEMICALS

No agrichemicals nor pesticides are detected in Yaeyama Chlorella as shown in JFRL's Analysis Certificate*.

BHC .......... Not detected (LD** 0.02ppm)
DDT ..........
Not detected (LD 0.02ppm)
Aldrin ........
Not detected (LD 0.01ppm)
Dieldrin ....
Not detected (LD 0.01ppm)
Endrin .......
Not detected (LD 0.01ppm)
EPN ...........
Not detected (LD 0.05ppm)
Parathion ......
Not detected (LD 0.05ppm)

*Analysis Certificate No.103044178-002 dated May 20, 2003 issued by Japan Food Research Lab.

**LD= Minimum limit of determination





Chlorella Production Process

Yaeyama Chlorella Cultivation Method (Patent No.3277372) was registered for patent by the Japan Patent Office on February 15, 2002.

Yaeyama Factory has developed and established their manufacturing technologies to let their outdoor sunray cultivation system boost up the contents of photosynthetic pigment (= Chlorophyll, carotenoid etc.) in the higher grade of their Chlorella products throughout the year. Chlorophyll works to exhaust dioxin out of the body, and carotenoids like beta-carotene, lutein, etc. function as a antioxidant to combat surplus super oxides.




Yaeyama Chlorella can be recommended to those who..........
want to be in a daily healthy life.
want to maintain vigor and beauty.
are liable to eat less fresh vegetables than needed.
are having a habit of taking irregular meals.
tend to take unbalanced diet.


Daily Dosage:

Chlorella tablets:-
Take 10 to 40 tablets (=2.0 g to 8.0 g), in case of 200mg tablets, in water or other drinks.
(In case of 500mg tablets, you can take 4 to 16 tablets.)

Chlorella powder:-
Take one or two spoonful of chlorella powder into water, milk or yogurt and stir well.
(one spoonful = 2.0g to 3.0g)



Yaeyama Chlorella Giant Pools












FERMENTED RICE GERM EXTRACT POWDER

GMT-SOD(=Super Oxide Dismutase) Pure Powder





Due to stress, atmospheric pollution, food additives, etc., surplus Super Oxides are produced in the body, obstructing the normal parts of the body. When this occurs, the enzyme named SOD (Super Oxide Dismutase) is generated to combat the surplus Super Oxides.
As one gets old, his ability to produce this SOD diminishes and geriatric degenerative disease will result.It also influences children's imperfect immunity. Nowadays, most people have an SOD deficit in the stress-ful environment.
WHAT IS GMT-SOD?
GMT-SOD is processed from the extract of fermented rice germ. It has a very strong SOD like activity.For easy absorption, it is produced in low molecular weight, namely, below 4000.
It can be used for all types of drinks, tablets, capsules, candy, etc.

SPECIFICATIONS
color........white or light yellow
moisture......not more than 8.5%
arsenic (as As2O3)....not more than 2.0ppm
lead.........not more than 0.4ppm
cadmium......not more than 0.1 ppm
tin..........not more than 25.0 ppm
aerobic plate count....not more than 3000/g
coliform organisms.....negative


FORMULATION/DOSAGE:
Hard capsule, tablet (w/binding agents like dextrin,lactose)
Recommended dosage is 300mg to 600mg per day.


Note:
The materials are liable to absorb humidity.
In case of tabletization, it is necessary to add binding agents like dextrin, lactose, etc. to make a tablet solid enough. It depends of tabletizing pressure of the machine, size of tablets, binding agents. It is needed to actually try to tabletize while adjusting tabletizing pressure on the machine. Can use approx. 60% of the materials as maximum plus the rest ingredients to make it tabletized.











SOY BEAN ISOFLAVONE

Antiestrogenic, Antifungal, Antiviral and Antioxidant Activities







Soybean is not widely consumed as food source in the West, but it is very important food in Japan and Asian countries. Isoflavones are found in soybeans in large amount and contain phytochemical compounds with antiestrogenic, antifungal, antiviral and actioxidant activities.

Isoflavone-intake serves to protect osteoporosis since soybean isoflavones suppress bone resorption.

Etiologic data show that higher frequency of prostatic carcinoma was found in white and black people than Japanese. The Finnish people's blood contains less isoflavone than Japanese. The isoflavone contents in blood is related to carcinogenesis. It was found that it keeps a mouse liver from nitrosoamine-induced cancer to feed a soybean diet. Also, biochemical data supported these observations. One of isoflavones, Genistein, shows to inhibit the growth of human breast cancer cell, tyrosine protein kinases and to block angiogenesis. Thus, isoflavone has potentiality for protection of carcinogenesis.



SPECIFICATIONS for Soy Bean ISOFLAVONE-10
* Soy Bean ISOFLAVONE-10 contains not less than 10.0% of isoflavone glycosides on dry matter.
Description:........Pale yellow powder
Purity Test
(1) Heavy metals ........ less than 20 ppm
(2) Arsenic ............. less than 2 ppm
Loss on drying .......... less than 6.0% (per gram, 105 deg.C., 1 hr)
Ash ..................... less than 5.0% (per gram)

CONTENTS OF ISOFLAVONE GLYCOSIDES

TOTAL ................... not less than 10.0%
DAIDZEIN GLYCOSIDES ..... 4.0 to 6.0%
GLYCITEIN GLYCOSIDES .... 2.0 to 4.0%
GENISTEIN GLYCOSIDES .... 1.0 to 3.0%


Note:

Weight accurately approx. 100mg and add in 20ml of methanol/sulfuric acid/water (8:1:1). Dissolve, dilute with methanol to exactly 50ml. Stopper tightly and heat for one hour at 100 deg. C. Cool and filter this solution(=the Sample Solution).

Weigh accurately approx. each 2mg of Daidzein and Genistein (supplied by SIGMA CHEMICAL COMPANY), dissolve in 50ml of methanol(=the Standard solution).

Inject 10 micro liter of each solution to High Performance Liquid Chromatograph (HPLC) respectively. Measure the peak areas of Daidzein, Glycitein and Genistein on the chromatograms of the sample solution and Daidzein and Genistein on the chromatograms of the Standard solution.

Operating conditions of HPLC
Column..... Shiseido Capcell Pak C18 (4.6 x 150mm)
Mobile phase ... 0.1% Trifluoroacetic acid solution/Acetonitrile = 75/25
Flow rate....... 1.0ml/min.
Detector ....... UV Absorption 260nm


ANALYSIS CERTIFICATE (for Lot #78130)

Description .............. Pale yellow powder
Purity Test
(1)Heavy Metals ....... Less than 20 ppm
(2) Arsenic ........... Less than 2 ppm
Loss on Drying ....... 3.1%
Ash .................. 1.3%

Content of Isoflavone Glycosides ........ 10.1%
(1) Daidzein Glycosides ...... 5.2%
(2) Glycitein Glycosides ..... 3.0%
(3) Genistein Glycosides ..... 1.9%

Microbial Limits
(1) Total aerobic plate count ...... Less than 1000 count per gram
(2) E. Coli ........................ negative


DOSAGE:

Recommended daily dosage is 150mg to 200mg as material.










AGARICUS BLAZEI MURILL EXTRACT POWDER

Activates the human immune system





Agaricus originates from Piedade in the suburbs of Sao Paulo, Brazil. About 3 decades ago, one American researcher got aware of the fact that the inhabitants in this area were rarely inflicted by adult diseases and they eat Agaricus on daily diet. It was called "Cogmelo de Deus" locally which means "God's mushroom".
It was the same time that Agaricus was firstly brought into Japan by Dr. Shoji Shibata, a professor in the Pharmacological Dept of Tokyo University. Another professor named Dr. Tetsuo Ikegawa of the National Cancer Center jointly worked with Dr. Shibata on the pharmacological effects of Agaricus. The research findings were announced at the General Convention of the Japan Pharmacological Association and the Japan Cancer Association. Their experiments utilizing mice showed that the polysaccharide beta-glucan contained in Agaricus significantly activated the immune system.




GASTRONOMIC EFFECTS

Agaricus Blazei Murill strengthens the immune function of inhibition for carcinomatous growth and activates natural killer cells. Among other components in Agaricus, the known anti-tumor agents are Beta-glucan and other polysaccharides which are highly concentrated in the powdered extract of Agaricus.

Polysaccharide contained in Agaricus Blazei Murill vitalizes generation of interferon and interleukin in guinea pigs. This effect indirectly functions to hold down proliferation of cancer cells. Also, it prevents viruses and other external matters from invading the tissue.

Clinical findings obtained jointly with universtity and hospital researchers were announced at the General Convention of the Japan Cancer Association in 1980. They showed that polysaccharide of Agaricus Blazei Murill is effective against Ehrlich's ascites carcinoma sigmoid coloniccancer, ovarian cancer, breast cancer, lung cancer and liver cancer as well as against solid cancer.

The findings also show that it activates metabolism by revitalizing normal biological tissue. Digestive enzymes such as amylase trypsin martase and the protease contained in fungus also enhances digestion. Besides, tyrosinase which oxydizes tyrosine and produces melanin, has a hypotensive effect. Furthermore, melanin protein that is effective in the generation of semen, hair and egg white was just recently discovered in Agaricus Blazei Murill.

Its physiological effects are anti-tumor, anti-allergic action and reduction of blood sugar level.


SPECIFICATIONS

Description........................ Brown or dark brown powder
Moisture (Vacuum Oven method)...... not more than 8.5%
Heavy Metals (as Pb)............... not more than 20 ppm
Aerobic Plate Count ............... not more than 300/g
Coliform Organisms................. negative
Protein (N x 6.25)................. 15.1%
Fat ............................... 0.1%
Fiber ............................. 0%
Ash ............................... 5.1%
Non-fibrous carbohydrate .......... 73.8%


FORMULATION/DOSAGE:

Hard capsule, tablet(w/binding agents like dextrin,lactose), granule
Recommended daily dosage is 3g to 5g as material.









WHEAT GERM OIL

Containing Vegetable Ceramides




Wheat germ oil has been applied to cosmetics and foods for a long time. It contains glycolipids including ceramides, namely, natural moisturizing components. In accordance with the Standards for Cosmetic Component Descriptions, Wheat germ oil (Component Code 522034) is widely usable in creams, milky lotions, gels, shampoos, etc.




SKIN & MOISTURIZING

Functions of skin:
(1) to prevent evaporation of the moisture from the body.
(2) to defense against external irritations and invasion of bacteria, etc.

Skin Structure and Moisturizing:
The skin is roughly classified into epidermis, corium and hypoderm. The epidermis consists of horny layer (=the outermost layer), granular layer, spinous layer and basal layer. In particular, the horny layer in the epidermis is largely related to the flexibility of the healthy skin. The flexibility (or moisturizing) of the skin is maintained by the moisture contained in this horny layer.

Horny Layer Components and Moisturizing:
"Ceramides" are largely contained in the lipids constituting the horny layer. Namely, ceramides amount to approx. 40% of the intercellular lipids in the human horny layer, and play the major part in moisturizing the human skin.


CERAMIDES & GLYCOLIPIDS

Ceramides:
In general, a ceramide has a structure in which a fatty acid is bonded to sphingosine. In ceramides originating in wheat, sugars like mannose and glucose are further bonded to glycolipids. In human and animal bodies, ceramides are generated in the skin, blood, brain, spinal cord and nerve tissue, whereas in plants, they are generated in wheat, rice, soybean, maze, spinach, etc.

Glycolipids:
Substances containing both of sugar and lipid in a molecule are generally called glycolipids. Glycolipids are widely found in animal and plant bodies including human body and are regarded as essentially necessary in the activities of living organisms because of being important constituents of biomembranes.


FUNCTIONS OF CERAMIDES

Relief of Dry Skin:
Normal human horny layer contains from 10 to 30% moisture. When the moisture content in the horny layer is lowered to 10% or below due to some external reasons, the skin becomes less elastic, coarse and chapped. Such conditions may be relieved not merely by applying fats or oils to the skin but by feeding something capable of maintaining the moisture in the horny layer.

Relief of Aging & Atopic Dermatitis:
It is reported that ceramides contained in the horny layer are decreased when skin becomes more and more dried up through the progress of aging or the onset of atopic dermatitis.

Comparison with other Moisturizing components:
(1) Collagen and moisturizing: It is said that collagen which is a structural protein amounting to 70% of the corium, contributes tothe "tension" and elasticity of the skin.
(2) Hyaluronic acid and moisturizing: Hyaluronic acid which is known as a water soluble component of the skin, has been widely employed as a moisturizer in cosmetics.
(3) Ceramides and moisturizing: Recently, it is reported that not only water soluble moisturizing components but also intercellular lipids (i.e. ceramides) play important roles in moisturizing the skin.


CHARACTERISTICS OF "WHEAT GERM OIL-S"

Form:
It is in the form of a brown, viscous oil having the characteristic smell of germ oil.

Merits:
(1) It is completely made from wheat produced in Japan.
(2) It contains at least 6% of glycolipids including ceramides.
** The content of the ceramides in the glycolipids is not specified because no method hs been established for analyzing the content.
(3) It contains wheat germ oil as the major component (content: approx. 90%)

Functions:
(1) Moisturizing: When the moisture contnet in the human horny layer is determined by using a high frequency transmission moisture meter, it is found that an obvious moisturizing effect can be achieved by applying this product.
(2) Inhibition of collagenase: Collagen which is the major component of the corium is decomposed by an enzyme called collagenase. By adding this product, the collagenase activity is inhibited and thus collagen is stabilized.
(3) Suppression of POV(peroxide value): It is confirmed by a model experiment that an increase in POV can be suppressed by adding this product to foods and cosmetics.

Application Examples:
(1) To Cosmetics: In accordance with the Standards for Cosmetic Component Descriptions, wheat germ oil (Component Code 522034), it is widely usable in creams, milky lotions, gels, lotions, shapoos, etc.
(2) To Foods: It is applicale to soft capsules, drinks, yoghurts, jellies, gummy candies, candies, baked products such as breads, doughnuts, cakes and cookies, creams, etc.


SPECIFICATIONS for Wheat Germ Oil-S

Component Code No.522034
Acid value.............. not more than 10
Saponification value.... 180 to 200
Iodine value............ 115 to 140
Unsaponifiable matter value......not more than 6%
Heavy metals............ not more than 20 ppm
Arsenic................. not more than 2 ppm
Glycolipids............. more than 6%
Bacteriological assays:
Standard plate count ... less than 1000 cfu/g
Coliforms .............. negative
Agricultural chemicals - fenitrothion/malathion..... not detected


SPECIFICATIONS for Wheat Germ Extract Powder

Color................... light yellow to yellow powder
Moisture................ not more than 7%
Heavy metals (AS Pb).... not more than 20 ppm
Arsenic................. not more than 2 ppm
pH...................... 5.0 to 7.0
Bacteriological assays:
Standard plate count ... less than 1000 cfu/g
Coliforms .............. negative
Ash..................... less than 6%









CHITOSAN & GLUCOSAMINE POWDER

Physiological functions -
decreasing cholesterol, inhibiting fat absorption,
inhibiting blood pressure elevation and improving intestinal metabolism






Chitosan is a deacetylated derivative of chitin. It is polysaccharide found in nature with an amino group, contained in the shells of Crustacea such as crab, shrimp, etc. Chitosan is a white to light-red solid powder, insoluble in water, soluble in organic acid, but indigestible by human digestive enzymes. Therefore, it is one of the so-called dietary fibers.
The chemical structures of chitin, chitosan and glucosamine are shown below.








Crab shells are treated with dilute hydrochloric acid and dilute sodium hydroxide to remove calcium and protein. The product thus obtained is called chitin, and its further deacetylated product with concentrated sodium hydroxide is chitosan. Both chitin and chitosan are white to light-yellow or light-red substances with chemical structures quite similar to that of cellulose. Both are stable natural high molecular substances with strong inter-molecular binding force due to intramolecular amino group.
Glucosamine, a monosaccharide and component sugar of chitosan, can also be obtained by direct hydrolysis of chitin.




CHITOSAN AS FOOD MATERIAL

(1) It is a nitrogen-containing cationic polysaccharide found in nature, and is one of the water-soluble dietary fibers.

(2) Its physiological functions include decrease of cholesterol, inhibition of fat absorption, prevention of increases in blood pressure, and improvement of intestinal environment are expected.

(3) Its safety in humans, animals and microbes has been confirmed by experiments. Also, it has long been taken as a food.

(4) It is stable of itself when it is added to food.

(5) Its content can be analyzed even when added to food.



SPECIFICATIONS - Dietary Fiber Registration No.970301
Source............................. Shells of Crustacea such as crab and shrimp
Appearance......................... White to light-red powder or flake
Water content...................... 10% maximum
Dilute acid insoluble.............. 1% maximum (calculated as dried matter material)
Viscosity.......................... 20mPa.s minimum
Degree of deacetylation............ 80% minimum
Ash................................ 1% maximum (calculated as dried material)
Arsenic ........................... 1 ppm maximum
Heavy metals....................... 5 ppm maximum as Pb
General bacterial count............ 3 x 1000/g maximum
Coliform bacilli................... negative

FORMULATION/DOSAGE:

Hard capsule, tablet (w/binding agents like dextrin,lactose), granule
Recommended daily dosage is 1.2g to 1.5g as material.



Chitosan Powder/Product Number
FL-80
FM-40
FM-80
FH-80
FM-200
Appearance
white to light-yellow powder
Particle size
80 mesh(98%mini)
40 mesh(95%mini)
80 mesh(95%mini)
80 mesh(95%mini)
200 mesh(95%mini)
Loss on drying
10% max
10% max
10% max
10% max
10% max
Residue on ignition
1% max
1% max
1% max
1% max
1% max
Viscosity
15mPa.s max
10-100mPa.s
10-100mPa.s
100mPa.s max
150mPa.s max
Degree of deacetylation
80% mini
80% mini
80% mini
80% mini
80% mini
Microbial
3x103 cells/g max
3x103 cells/g max
3x103 cells/g max
3x103 cells/g max
3x103 cells/g max
Coliforms
Negative
Negative
Negative
Negative
Negative
Heavy metals
10 ppm max
10 ppm max
10 ppm max
10 ppm max
10 ppm max
Arsenic
1 ppm max
1 ppm max
1 ppm max
1 ppm max
1 ppm max
Total chromium
-
-
-
10 ppm max
-
Characteristics
Low viscosity product
-
-
Standard of JHFA
-






Glucosamine Hydrochloride

Glucosamine, an amino monosaccharide which forms chitosan, is one of the biological components approved as a food additive in Japan. Biologically, it is present mainly as a component of mucoprotein distributed in connective tissues such as cartilage, synovial fluid, blood vessel walls, etc. Glucosamine has been claimed to be effective as a treatment for osteoarthritis both by injection and oral administration, and in Europe and America it has been actively used in various ways in medical drugs and health foods. (Glucosamine hydrosulfate is also available.)


Item
Standard
Item
Standard
Appearance
white crystals
Specific rotation
72+-2Ą
Loss on drying
0.5% max.
General viable
bacterial count
3x103 counts/g max.
Residue on ignition
0.1% max.
pH (10%)
3 to 5
Coliforms
Negative
Assay
97% max.
Arsenic
0.5 ppm max.
Chlorine
16% to 18%
Heavy metals
10 ppm max.









Click and see!

Chitosan Hard Capsule






Glucosamine Tablets













PERILLA SEED EXTRACT POWDER & LIQUID

Effective anti-allergy substance

** Perilla Leaf Extract Powder is also available.



What is Perilla Seed ? Perilla frutescens and a lot of herbs like lavandula belong to Fam. LABIATAE. Perilla seed has been cultivated in Japan, China, Korea and Southeast Asia and used as spices and also main supply for ƒż-linolenate rich oil.
The patients with allergy are increasing every year, and the diet is said to be one of the most important factor of this disease. Daily intake of n-6 fatty acids, contained in meet or plant oil such as safflower, are accumulated as arachidonic acid which is converted to allergic mediators. PERILLA SEED EXTRACT inhibits the production of allergic mediators, termed leukotrienes (LTs). The mediators are metabolites of arachidonic acid through 5-lipoxygenase (5-LO) pathway. PERILLA SEED EXTRACT selectively inhibits 5-LO activity (in vitro). PERILLA SEED EXTRACT also inhibits type IV allergy as well as TPA-induced inflammation (in vivo). Moreover, the serum IgE levels were suppressed by administration of PERILLA SEED EXTRACT, and allergic rhinitis, hay fever and urticaria were significantly improved on human.



Product Standards for Perilla Seed Extract

The effective components, flavonoids in polyphenol, are extracted from perilla (perilla frutescens var. japonica or crispa) seeds in ethanol.
**Perilla Seed Extract - L (liquid) is also available.


SPECIFICATIONS for Perilla Seed Extract - P (Powder)

Appearance..... yellowish powder with bitter taste
Identification..... yellow (DAVIS method)
Content of Polyphenol..... more than 3% (Folin-Denis method)
Loss on drying..... less than 5% (Analysis for Hygienic Chemists,1g, 105Ž, 2h)
Standard plate counts..... less than 3,000 cells/g (Analysis for Hygienic Chemists)
Coliforms..... Negative (Analysis for Hygienic Chemists)
Arsenic..... less than 1 ppm (Standard Methods of Analysis in Food Safety Regulation)
Heavy metals..... less than 10 ppm (The Japanese Standards for Food Additives)
Moulds and Yeasts..... less than 1,000 cells/g (Analysis for Hygienic Chemists)

** Certification Test to 1.0g of this product, add 8.5ml of 90% diethlene glycol and 0.5ml of 1N NaOH.
Then a yellow color develops. (DAVIS method)


SPECIFICATIONS for Perilla Seed Extract - L (Liquid)

Appearance..... dark brown liquid with bitter taste
Content of Polyphenol..... more than 2% (Folin-Denis method)
Residue on Evaporation..... in the range of 18 to 22% (Analysis for Hygienic Chemists)
Standard plate counts..... less than 3,000 cells/g (Analysis for Hygienic Chemists)
Coliforms..... Negative (Analysis for Hygienic Chemists)
Arsenic..... less than 1 ppm (Standard Methods of Analysis in Food Safety Regulation)
Heavy metals..... less than 10 ppm (The Japanese Standards for Food Additives)
Moulds and Yeasts..... less than 1,000 cells/g (Analysis for Hygienic Chemists)

** Certification Test to 1.0g of this product, add 8.5ml of 90% diethlene glycol and 0.5ml of 1N NaOH.
Then a yellow color develops. (DAVIS method)



Residual Agricultural Chemicals
Assayed Items       Results       Detection Limits      Assay Method       
   BHC            Not Detected      0.02ppm           Gas Chromatography
   DDT            Not Detected      0.02ppm           Gas Chromatography
   Aldrin         Not Detected      0.01ppm           Gas Chromatography
   Dieldrin       Not Detected      0.01ppm           Gas Chromatography
   Endrin         Not Detected      0.01ppm           Gas Chromatography
   Diazinon       Not Detected      0.05ppm           Gas Chromatography
   Parathion      Not Detected      0.05ppm           Gas Chromatography
   Malathon       Not Detected      0.05ppm           Gas Chromatography

     Tested by: Japan Food Research Center Foundation
     Research results issue number 397060549-002



          PERILLA SEED EXTRACT-P (powder) 100 - 150mg/day
             PERILLA SEED EXTRACT-L (liquid) 150 - 225mg/day

Perilla "Leaf" Extract Powder is also available.


Product Standards for Perilla Leaf Extract Powder

MATERIAL

The material used is limited to Perilla leaf from Hokkaido (Japan) from the view point of its quality, its anti-allergic effects and the control of its production. The variety used in the manufacturing process is Perilla frutescens var. acuta Kudo forma viridis Makino.


EXTRACTION OF PERILLA LEAF

The decoction of the dried leaves afforded by boiling water gives an extract with greater anti-allergy activity than that obtained using aqueous ethanol and avoids the precipitation problems caused by chlorophyll etc., in the aqueous ethanol extract (Kosuna et al., 1994).


SPRAY DRYING

By the addition of dextrin to the aqueous Perilla extract, followed by spray drying, a stable powdered form is achieved, namely, Perilla extract powder with 1g equivalent to 1ml of Perilla extract. This powder is available for capsule and tablet formulations and for use in a range of health products.


MANUFACTURING PROCESS

Dried Perilla Leaves .....Extracted with boiling water .....Filtrate.....Purified.....Sterilized .....Added ethanl (for preservation) .....Product ..... Filling

SPECIFICATIONS for Perilla Leaf Extract Powder

Appearance........................ Light brown powder
Moisture ......................... less than 4.0%
Protein .......................... less than 1.4%
Fat .............................. less than 0.3%
Carbohydrate ..................... 94.0 to 98.0%
Ash .............................. less than 0.3%
Sodium ........................... less than 0.05%
Arsenic .......................... not detected (less than 0.2 ppm)
Heavy Metals (as Pb).............. not detected (less than 10 ppm)
Number of bacteria ............... less than 3,000 cfu/g
Coli-aerogenes group ............. negative









Barley Leaves Extract Powder 100%





PRODUCT INFO:

Barley young leaves extract powder richly contains edible fiber, carotin, chlorophil, SOD, vitamins and minerals....... It tastes good and easy to eat and drink with water and milk.

Specifications (per 100g):

Appearance Light green to dark green color powder
Smell Similar to green powdered tea
Loss on drying not more than 5%
Total chlorophyll not less than 180mg/100g
Total pheophorbides not more than 30mg/100g
Endrin not detected
Dieldrin not detected
Aldrin not detected
Parathion not detected
PCB not detected
Arsenic not more than 2ppm
Heavy metals not more than 20ppm
Aerobic plate count not more than 3.0 x 103/g
Coliform bacillus negative

Certificate of Analysis for a particular lot (per 100g):

Water 1.9% Iron 70.5mg
Protein 22.0% Copper 7.47ppm
Fat 7.9% Zinc 16.3ppm
Fiber 20.4% Total pheophorbides 4mg/100g
Ash 6.3% Endrin not detected
Carbohydrate 41.5% Dieldrin not detected
Edible fiber 52.1% Aldrin not detected
Vitamin A 7,560IU/100g Parathion not detected
Total chlorophyll 881mg PCB not detected
Calcium 336mg Arsenic not detected
Sodium 171mg Heavy metals not detected
Magnesium 123mg Aerobic plate count 1.7 x 103/g
Kalium 1.74g Coliform bacillus negative





COMPARISON:

[100g of Barley Leaves Extract Powder vis-a-vis 100g of Other Foods (Drink)]

1. Edible Fiber
(= the 6th nutrient essential to present diet)
Barley Leaves Extract Powder contains 52.1g of edible fiber, whereas burdock and potate contain 2.2g and 0.9g respectively. This means Barley Leaves Extract Powder contains edible fibers 23.7 times and 57.9 times as much as burdock and potate.

2. Carotene (Vitamin A1)
(= taken into the body to convert to vitamin A)
Barley Leaves Extract Powder contains 18.3mg of carotine, whereas carrot and leek (scallion) contains 7.3mg and 3.3mg each. Barley Leaves Extract Powder contains carotine 2.5 times and 5.5 times as much.

3. Calcium
(= essential for growth of bones and teeth and smooth function of human body)
Barley Leaves Extract Powder contains 336mg of calcium, whereas milk and sardine contains 100mg and 70mg each. Barley Leaves Extract Powder contains 3.4 times and 4.8 times as much.

4. Potassium
(= liable to be short for heavy drinker, sweets eater and diet practicin)
Barley Leaves Extract Powder contains 1,740mg of potassium, whereas seaweed and cucumber contains 730mg and 210mg each. Barley Leaves Extract Powder contains 2.4 times and 8.3 times as much.

5. Iron
(= a kind of mineral, contained in red blood corpuscle, muscle, liver)
Barley Leaves Extract Powder contains 70.5mg of iron, whereas pork lever and spinach contains 13.0mg and 3.7mg each. Barley Leaves Extract Powder contains 5.4 times and 19 times as much.


MANUFACTURING PROCESS:

Washing Ë Blanching Ë@Drying Ë Crushing Ë Sterilizing Ë Final Products
FORMULATION/DOSAGE:

Barley Leaves Extract Powder -- Average dosage: 2.5g to 5g per day.
Encapsulation is not recommended due to its high humidity absorption.

WARNING:

Storage: keep it in dark and cool place, not being exposed to direct sun ray, otherwise it may get decolored by light and heat. If it is mixed with acidic stuff, it may also get decolored.













GREEN TEA EXTRACT POWDER - CATECHIN

POLYPHENOLS - "POLYPHENON 60-30-G"





Recently, tea polyphenols, the major components of the soluble constituent of tea were fractionated and purified. After intensive research, tea polyphenols were proved to be multi-functionally effective in preventing putrefaction or rancidity of foods, infection of alimentary or respiratory diseases, occurrence of cardio-vascular diseases or development of malignant tumors.





Functions of tea polyphenols experimentally proved:

antioxidative action on edible fats and oils
antibacterial action against foodborne bacteria
anticarious action
antitoxic action against Clostridium botulinum toxin
inactivation of influenza virus
inhibition of ƒż-amylase and sucrase
suppression of blood glucose increase
inhibition of angiotensin I converting enzyme
suppression of hypertension and brain stroke
suppression of cholesterol and fat increase
antiulcer action
radio-protective action
antimutagenic action
antitumor action
molluskcidal action
deodorant action etc.


FORMULATION/DOSAGE:

Hard capsule contains approx.170mg of Polyphenon 60. If this capsule size is too small, you can add approx.80mg of lactose, totalling 250mg capsule. Average dosage: 3 capsules per day. Drying agent should be contained in the bottle.




POLYPHENON 60 - 100% Natural Green Tea Extract Powder

Appearance..............Yellowish brown
Total catechins.........60% min.
PH of 1% solution.......4.0-6.0
Moisture................8% max.
Total ash...............5% max.
Arsenic (as AS2O3)......2ppm max.
Heavy metals............20ppm max.
Aerobic plate count.....1,000CFU/g max.
Coliform................negative
EGCg (HPLC Method)..... 28.2% (w/w) Lot No.9803251
**EGCg=Epigallocatechin Gallate


POLYPHENON 30

Appearance..............Yellowish brown
Total catechins.........30% min.
PH of 1% solution.......4.5-6.5
Moisture................8% max.
Total ash...............10% max.
Arsenic (as AS2O3)......2ppm max.
Heavy metals............20ppm max.
Aerobic plate count.....1,000CFU/g max.
Coliform................negative
EGCg (HPLC Method)......17.0% (w/w) Lot No.9712121


POLYPHENON G

Appearance..............Yellowish brown
Total catechins.........25% min.
PH of 1% solution.......4.5-6.5
Moisture................8% max.
Total ash...............10% max.
Arsenic (as AS2O3)......2ppm max.
Heavy metals............20ppm max.
Aerobic plate count.....1,000CFU/g max.
Coliform................negative
EGCg (HPLC Method)......14.5% (w/w) Lot No.9808191









BLUEBERRY EXTRACT POWDER

Bilberon-25 (Bilberry Anthocyanidins 25%)





Blueberry (Vaccinium myrtillus), a genus of Vaccinium of azalea family is a shrubby perennial plant.For a long time, extract from the berries and the leaves has been used for treatment of scurvy, urinary diseases and diabetes. Physiological function of Vaccinium myrtillus was found by British airforce pilots during World War II who told experiences that one who habitually had blueberry jam could see objects better even during the twilight flights.




PHYSIOLOGICAL FUNCTIONS OF BLUEBERRY EXTRACT

Accelerating re-synthesizing rhodopsin in retinae
Accelerating adaptability of visual sense in the darkness
Protection of capillary blood vessels
Anti-tumor effect
Improvement of circulatory system functions
Anti-inflammatory effect
Free radial scavenger activity


COMPOSITION OF BLUEBERRY EXTRACT

As biologically active substances, Vaccinium myrtillus anthocyanosides (= VMA), are known. There are five different kinds of anthocyanosides, each combined with one of three different saccharides. Thus, 15 different VMAs are identified in total.


FUNCTIONS OF BLUEBERRY EXTRACT

In Europe and U.S.A., blueberry extract is widely used as medicine for blood vessel troubles, diabetes and blood circulatory diseases, and for eyes.

treatment and prevention for heart diseases and celebral vascular diseases
treatment and prevention for diabetes
prevention of eye strain
food coloring


FORMULATION/DOSAGE:

Hard Capsule; Average dosage:100mg per day



BILBERON-25 (Bilberry Anthocyanidins 25%)

BILBERON-25 is extracted and purified anthocyanosides of fresh Bilberry (Vaccinium myrtillus) fruit. It contains more than 25% of anthocyanidins calculated on dry matter.

Description..................Red brown powder with acidity taste
Arsenic (as AS2O3)...........4ppm max.
Heavy metals (as lead).......40ppm max.
Free anthocyanidins..........5% max. by HPLC method
Residue on ignition:.........3% max.
Water content................5% max.
Assay........................more than 25% as DELPHINIDIN










SHIITAKE L.E.M.

Lentinus Edodes Mycelia






L.E.M. extract contains lots of bio-active substances such as polysaccharide protein, nucleic acid derivatives, vitamin B group, ergosterol, erytadenine, and various minerals. L.E.M. extrat improves and activates the organ's defence functions**. Especially, the action of erytadenine, very unique to lentinus edodes is quite marked in preventing the accumulation of cholesterol and protecting from arteriosclerosis.



Organ's Defence Funtions

expel micro-organisms of external origin including bacteria, fungi, viruses and protozoa.
expel harmful chemial substances (residual agricultural chemicals, environmental pollutants, food additives), pollen and dust.
expel abnormal cells (mutant cells, cancer cells)
expel worn out autocells (old erythrocytes, etc.), excessively produced substances (antigen antibody complexes), etc.


Physiological Activity of L.E.M.

Protection against bacterial infection
Lymphocyte blastogenic activity
Promotion of chemotaxis in macrophages
Anti-HIV action
Anti-tumor effect
Medicational effect against woodchuck hepatitis
Influence on reverse transcriptase activity
Inhibitive effect on proliferation of rat ascites hepatoma
L929 cells cytotoxicity
In vivo neutrophil conglomerating activity


CERTIFICATE OF ANALYSIS (NO.19010885-002)

Moisture ....................0.3%
Protein .....................26.1%
Fat .........................1.4%
Fiber .......................0.7%
Ash ..........................24.4%
Sugar .......................47.1%
Calcium ....................75.0mg/100g
Vitamin B1 ...................0.24mg/100g
Riboflavin ...................1.27mg/100g
Arsenic ......................3.22ppm
Heavy metal (as Pb) ..........2.30ppm
Phenitrotion (MEP) .........not detected
Diadinon ...................not detected
Aerobic plate count ........4.1 x 104/g
Coliform organisms ...........negative










GINKGO BILOBA EXTRACT
(Ginkgoflavonglycosides 24%)





Modern science validates health benefits of ancient herb - Ginkgo Biloba.
By adding Ginkgo Biloba's array of powerful constituents to your diet, you can:

IMPROVE brain function, memory retention and mental clarity;
INCREASE blood flow and oxygen supply;
STRENGTHEN the cardiovascular system;
REDUCE deterioration of nerves and the cells that protect them;
NEUTRALIZE free radicals that damage cellular health and accelerate aging;
PREVENT water retentionin delicate tissues;
STABILIZE cellular energy production;
ENHANCE drainage of cellular and circulatory waste products;
INCREASE blood circulation throughout the entire body.




CERTIFICATE OF ANALYSIS (NO.45042229-002)

Descriptions:.......light brown to brown powder,herb-like odor, bitter taste
Identification:...........a) Red color with Zn/HCL,b) Fingeprint - HPLC
Properties:...............pH-value 3.5 - 5.0 (1% in water)
Solubility:............... 4g extract soluble in 100ml 50% ethanol
Purity:
Protein (N x 6.25).............0.7%
Fat (method with soxhlet extractor).....2.8%
Fiber..........................0.1%
Arsenic...........not detected (MLD 0.1ppm)
Heavy metal (as Pb)..........not detected (MLD 1ppm)
Mercury......................not detected (MLD 0.01ppm)
Loss on drying...............5% max.
Residue on iginition.........1% max.
Total bacterial count........300/g max.
Pathogenic germs.............none
Radioactivity................free
Ginkgolic acid ................ less than 1 ppm

Assay:
Ginkgoflavonglycoside 24% - 25%
Quercetin 380mg/100g
Kaempferol 370mg/100g
Isorhamnetin 66mg/100g









OYSTER EXTRACT POWDER
OYSTER EXTRACT MARINE ZINC POWDER





Oyster Extract Powder is oyster meat extract powder processed from fresh oyster and contains such important nutrients as glycogen, taurine, zinc, etc.




MANUFACTURING METHOD:

Fresh oyster meat ¨ Extraction with pressure ¨ Filtration ¨ Concentration under vacuum ¨ Sterilization ¨ Spray drying ¨ Powder

SPECIFICATIONS

Characteristics: Light yellowish hygroscopic powder with some characteristic odor but no nasty smell.
Loss on drying..... Not more than 6%
Protein............ Not less than 20%
Glycogen........... Not less than 25%
Taurine............ Not less than 3.5%
Zinc............... Not less than 180 ppm
Ash................ Not more than 20%
Paralytic shellfish poison..... Negative
Diarrhetic shellfish poison.... Negative
Total Drin (Dieldrin, Endrin, Aldrin)..... Negative
Heavy metal (Pb)... Not more than 20 ppm
Arsenic(As2O3)..... Not more than 2 ppm
Aerobic plate count..... Not more than 3000/g
Coliform organism (BGLB broth).........negative


Certificate of Analysis (g/100g)(for a certain lot)

Moisture (uner pressure 10mmHg).............1.9%
Protein (N x 6.25).........................26.3%
Fat (Soxhlet extract).......................0.3%
Ash.........................................8.0%
Non-fibrous carbohydrate...................63.5%
Energy**..................................362 kcal/100g
** factors for calculating energy value: protein 4, fat 9, carbohydrate 4 (non-fibrous carbohydrte + fiber)
Riboflavin...........................1.66mg/100g
Vitamin B6...........................0.16mg/100g
Vitamin B12.........................82 microgram/100g
Biotine..............................8.7 microgram/100g
Inositol............................108mg/100g
Choline..............................0.46%
Folic acid..........................70 microgram/100g
Phosphorus.........................590mg/100g
Iron................................5.00mg/100g
Calcium..............................61.8mg/100g
Sodium................................1.59%
Potassium..............................1.43%
Selenium..............................1.19ppm
Copper..............................6.58ppm
Zinc.................................176ppm
Manganese............................9.50ppm
Cobalt...............................0.18ppm
Iodine...............................2.7mg/100g
Magnesium...........................222mg/100g

Amino Acid Composition (g/100g)
Arginine..........0.72
Lysine...........0.89
Histidine..........0.40
Phenylalanine......0.32
Tyrosine..........0.26
Leucine..........0.66
Isoleucine.........0.41
Methionine........0.33
Valine...........0.59
Alanine..........1.30
Glycine..........1.31
Proline...........2.10
Serine............0.54
Threonine..........0.69
Spartic acid........1.30
Tryptophane........0.10
Cystine...........0.17
Glutamioc acid......2.42
Taurine...........3.17%
Glycogen..........29.4%
Germanium........not detected
PCB.............not detected










COENZYME Q10
(UBIDECARENONE or UBIQUINONE 10)

..... generating energy within the body's cell






Chemical Name:

2-(3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-
dimethoxy-3-methyl-1,4-benzoquinone


Molecular formula:

C59H90O4 (molecular weight: 863.36)
Ubidecarenone contains not less than 98.0% of C59H90O4, being calculated on the anhydrous basis.

Purpose: Raw material for preparation (Cardiotonic Agent)




CERTIFICATE OF ANALYSIS (NO.45042229-002)

Descriptions.......Crystalline powder, yellow to orange, odorless & tasteless
Identification.......1. Benzoquinone 2.IR-spectrum
Melting point ....... about 48 deg.C
Water solubility ...... insoluble
Heavy metal (as Pb)..........not more than 20ppm
Related substances ..........not larger than standard peak
Arsenic......................not more than 2ppm
Homologues of ubiquinone........not detected Q7, Q8
Ubiquinone-9 content (Co Q9).........not more than 0.5%
Other impurities ............ not detected
Foreign substances .......... not detected
Water content ............... not more than 0.2%
Residue on iginition......... not more than 0.1%
Assay ....................... 98.0 - 101.0%


It is needed to supplement the diet with Coenzyme Q10 for those who...
want to nourish their immune system
want to strengthen their heart
want to keep up vigor and youth

Hazardous Reactivity:
Instability: Stable at normal temperatures and storage conditions.
It gradually decomposes by light, and its color becomes deep.
Incompatibility: Incompatible with strong oxidizing agents.










Red Yeast Rice Powder
Red Yeast Rice Extract Powder




Red Yeast Rice is a relative of yeast rice that is used for fermented food, sake,soy sauce and miso paste, and as its name implies, it is red in color. It has been used inChinese herbal medicine since ancient times. The "Ben Cao Wang Mu", a Chinese treatise on herbal medicine, says that Red Yeast Rice aids the digestion and reinvigorates the blood an dstrengthen the internal organs and refreshes the stomach.

Thus, Red Yeast Rice has been found to have such beneficial effects as reducing blood pressure and LDL cholesterol that raises arteriosclerosis.




PRODUCTION PROCESS:






SPECIFICATIONS FOR Red Yeast Rice Powder
Item
IP-D
3P-D1
3P-D2
Properties
powder, red
powder, red
powder, red
Water
10% or less
10% or less
10% or less
GABA
0.025-0.050%
-
-
Monacolin K
-
0.1% or more
0.2% or more
Heavy metals (as Pb)
50 ppm or less
50 ppm or less
50 ppm or less
Arsenic (as As2O3)
2.5 ppm or less
2.5 ppm or less
2.5 ppm or less
Bacteria
300 or less/g
300 or less/g
300 or less/g
Eumycota (mold)
Negative
Negative
Negative
Escherichia coli
Negative
Negative
Negative



SPECIFICATIONS FOR Red Yeast Rice Extract Powder
Item
IE-D
3E-D20
Properties
powder, red
powder, red
Water
8% or less
8% or less
GABA
150mg/100g or more
-
Monacolin K
-
2.0% or more
Heavy metals (as Pb)
50 ppm or less
50 ppm or less
Arsenic (as As2O3)
2.5 ppm or less
2.5 ppm or less
Aerobic plate count
3000 or less/g
3000 or less/g
Coliform bacteria
Negative
Negative

Shelf life:
1 year after date of manufacture for 1E-D (unopened)
6 months after date of manufacture for 3E-D20 (unopened)


Cholesterol-lowering effect of Red Yeast Rice (3P-D1, 3P-D2 & 3E-D20)
Red Yeast Rice naturally has HMG-CoA reductase inhibitors, including Monacolin K, which has been associated with decreasing the level of LDL cholesterol.
Volunteer
(initial)
Sex
Age
Total cholesterol (mg/dl)
Change(%)
Start
2 weeks
4 weeks
2 weeks
4 weeks
K.S.
male
50
230
201
193
-13
-16
H.W.
male
42
240
196
204
-18
-15
T.O.
female
57
246
205
183
-17
-26
K.O.
female
69
257
224
213
-13
-17
M.T.
female
67
276
244
227
-12
-18
Average
-
-
250
214
204
-14.4
-18.8
In the volunteer test with using the patients of hyperlipidemia, when everyone took 4g of Red Yeast Rice every day, the average of LDL cholesterol decreased by 24% after 2 weeks, and by 32% after 4 weeks. Cholesterol-lowering effect of Red Yeast Rice was obtained at the Medical Department of Chiba Universtity.



Anti-hypertensive effect of Red Yeast Rice (1P-D2 & 1E-D)

On the basis of a large quantity of test data obtained through extensive research, we have confirmed that Red Yeast Rice is effective in reducing high blood pressure. Furthermore, Red Yeast Rice never has the side effects that the drugs have. You can use Red Yeast Rice in any food safely.







SAFETY DATA

Red Yeast Rice has been used from ancient times through the present day as a brewing material, an agent to add color and aroma to food, and a meat preservativce. Throughout this rich history as a food product, it has been consumed by a large number of people.It is produced with a clean solid fermentation technology according to the methods of yeast rice fermentation that has been used. None of the test animals shows any sign of suffering side effects from toxicity, mutagenesis, or fungal toxicity.

Item
Subject
Result
Oral acute toxicity test (Limit test)
mice
no abnormality after administering 2,000mg/kg
Oral acute toxicity test
mice
LD50 23.1g/kg or more
Mutagenesis test
bacteria
no mutagenesis
Fungal toxicity, 10 types
not detected











LUTEIN POWDER
Lutein-P80






Lutein-P80

This product is extracted and refined from flowers of Marigold (Tagetes erecta Willd).
It contains more than 80% of Lutein Esters.


SPECIFICATIONS for Lutein-P80:
Appearance
yellow orange powder and has unique smell
Content of Lutein Esters
more than 80%
HPLC Method
Content of Lutein (free)
more than 40%
HPLC Method
Content of Total Corotenoid Esters
more than 85%
UV Method
Content of Total Carotenoid (free)
more than 42.5%
UV Method
Loss on Drying
less than 5%
1g, 40deg.C reduced pressure
phosphorus Pentaoxide, 4h
Heavy Metals
less than 10 ppm
The Japanese Standard for
Food Additives
Arsenic
less than 1 ppm
Standard Methods of Analysis
in Food Safety Regulation
Standard Plate Counts
Max. 1 x 103 cells/g
Analysis for Hygienic Chemists
Moulds and Yeasts
Max. 1 x 102 cells/g
Analysis for Hygienic Chemists
Coliforms
Negative
Analysis for Hygienic Chemists


Composition
Ingredients
Contents
Marigold extract
99.75%
Natural tocopherols
0.25%






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