CHITOSAN & GLUCOSAMINE POWDER

Physiological functions -
decreasing cholesterol, inhibiting fat absorption,
inhibiting blood pressure elevation and improving intestinal metabolism







Chitosan is a deacetylated derivative of chitin. It is polysaccharide found in nature with an amino group, contained in the shells of Crustacea such as crab, shrimp, etc. Chitosan is a white to light-red solid powder, insoluble in water, soluble in organic acid, but indigestible by human digestive enzymes. Therefore, it is one of the so-called dietary fibers.

The chemical structures of chitin, chitosan and glucosamine are shown below.





Crab shells are treated with dilute hydrochloric acid and dilute sodium hydroxide to remove calcium and protein. The product thus obtained is called chitin, and its further deacetylated product with concentrated sodium hydroxide is chitosan. Both chitin and chitosan are white to light-yellow or light-red substances with chemical structures quite similar to that of cellulose. Both are stable natural high molecular substances with strong inter-molecular binding force due to intramolecular amino group.

Glucosamine, a monosaccharide and component sugar of chitosan, can also be obtained by direct hydrolysis of chitin.


CHITOSAN AS FOOD MATERIAL

(1) It is a nitrogen-containing cationic polysaccharide found in nature, and is one of the water-soluble dietary fibers.

(2) Its physiological functions include decrease of cholesterol, inhibition of fat absorption, prevention of increases in blood pressure, and improvement of intestinal environment are expected.

(3) Its safety in humans, animals and microbes has been confirmed by experiments. Also, it has long been taken as a food.

(4) It is stable of itself when it is added to food.

(5) Its content can be analyzed even when added to food.


SPECIFICATIONS - Dietary Fiber Registration No.970301
Source............................. Shells of Crustacea such as crab and shrimp
Appearance......................... White to light-red powder or flake
Water content...................... 10% maximum
Dilute acid insoluble.............. 1% maximum (calculated as dried matter material)
Viscosity.......................... 20mPa.s minimum
Degree of deacetylation............ 80% minimum
Ash................................ 1% maximum (calculated as dried material)
Arsenic ........................... 1 ppm maximum
Heavy metals....................... 5 ppm maximum as Pb
General bacterial count............ 3 x 1000/g maximum
Coliform bacilli................... negative


FORMULATION/DOSAGE:
Hard capsule, tablet (w/binding agents like dextrin,lactose), granule
Recommended daily dosage is 1.2g to 1.5g as material.



Chitosan Powder/Product Number
FL-80
FM-40
FM-80
FH-80
FM-200
Appearance
white to light-yellow powder
Particle size
80 mesh(98%mini)
40 mesh(95%mini)
80 mesh(95%mini)
80 mesh(95%mini)
200 mesh(95%mini)
Loss on drying
10% max
10% max
10% max
10% max
10% max
Residue on ignition
1% max
1% max
1% max
1% max
1% max
Viscosity
15mPa.s max
10-100mPa.s
10-100mPa.s
100mPa.s mini
150mPa.s mini
Degree of deacetylation
80% mini
80% mini
80% mini
80% mini
80% mini
Microbial
3x103 cells/g max
3x103 cells/g max
3x103 cells/g max
3x103 cells/g max
3x103 cells/g max
Coliforms
Negative
Negative
Negative
Negative
Negative
Heavy metals
10 ppm max
10 ppm max
10 ppm max
10 ppm max
10 ppm max
Arsenic
1 ppm max
1 ppm max
1 ppm max
1 ppm max
1 ppm max
Total chromium
-
-
-
10 ppm max
-
Characteristics
Low viscosity product
-
-
Standard of JHFA
-

Certificate of Analysis for Chitosan FM-200




Glucosamine Hydrochloride
Glucosamine, an amino monosaccharide which forms chitosan, is one of the biological components approved as a food additive in Japan. Biologically, it is present mainly as a component of mucoprotein distributed in connective tissues such as cartilage, synovial fluid, blood vessel walls, etc. Glucosamine has been claimed to be effective as a treatment for osteoarthritis both by injection and oral administration, and in Europe and America it has been actively used in various ways in medical drugs and health foods.
(Glucosamine hydrosulfate is also available.)
Item
Standard
Item
Standard
Appearance
white crystals
Specific rotation
72+-2
Loss on drying
0.5% max.
General viable
bacterial count
3x103 counts/g max.
Residue on ignition
0.1% max.
pH (10%)
3 to 5
Coliforms
Negative
Assay
97% max.
Arsenic
0.5 ppm max.
Chlorine
16% to 18%
Heavy metals
10 ppm max.






Click and see!

Chitosan Hard Capsule


Glucosamine Tablets






Back